Bed bugs are more than in your mattress, they infect every part of your house, the floors, bed frames, clothes, curtains, couch.. literally everywhere. If you wanted to get rid of it you could bomb and spray your house but that usually never works, the only way to be sure you get rid of them is to have your house heated with extreme temperature which kills all of them in one try, although it is expensive, its the only proven way to get rid of all of them.
As far as the bumps, if its not bed bugs, maybe its scabies. They itch really bad at night and after hot showers because the insects dig up your skin so they can breathe which irritate you and make it itchy, if there are red or white really small line around or near the bumps it could be scabies.
You can also develop allergic reactions even if you never had them before, or maybe you bought something as simple as a pot, pillow, or anything really that you could be allergic to.
You should get your doctor to do a skin scrap test which can let him know if it a parasite, allergic reaction, or some kind of disease. It can be expensive but sometimes that's the only accurate way to find out what it is.
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