Excedrin is a nonprescription medication that contains acetaminophen, aspirin, and caffeine. Aleve is a nonprescription nonsteroidal anti-inflammatory drug (NSAID) and its active ingredient is naproxen. The aspirin in Excedrin and the Aleve (naproxen) are similar medications and are used for similar things. Aleve itself can be used for a migraine. And Excedrin can be used as well.
If you are taking the Aleve chronically (all the time) for something other than migraine (like pain), and you have tried the Aleve for the migraine, and it hasn’t helped, then go ahead and try the Excedrin. You can take both together for a short period of time. The biggest side effect you might notice is increased bleeding or bruising.
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