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Answers From Experts & Organizations (1)

Internal Medicine
Emory University
131 Answers
113,365 Helpful Votes

MCHC stands for mean corpuscular hemoglobin concentration. It’s the concentration of hemoglobin in the body’s red blood cells. MCHC is calculated by automated cell counters and may be reported as part of a complete blood count (CBC) test.

The MCHC may be low in certain forms of anemia (such as iron-deficiency), normal in others ([vitamin] B12 deficiency), and high in other blood disorders (hereditary spherocytosis).

Falsely high and falsely low results on an MCHC test are common. Doctors only use the MCHC to provide clues or as supporting information, not to make a diagnosis. Many people with abnormal MCHC values have nothing seriously wrong with their blood.

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