My WebMD Sign In, Sign Up

Ask Your Question

WebMD Answers

120 Characters remaining
120 Characters remaining
  • First, try and keep your question as short as possible.
  • Include specific words that will help us identify questions that may already have your answer.
  • If you don't find your answer, you can post your question to WebMD Experts and Contributors.


Posted: | Report This Report Question |

Can I take St. John's wort safely with metformin, enalapril, simvastatin, HCTZ, and omega-3 fish oil?

Related Topics: St. John's Wort, Fish, Oil, Omega-3

Answers From Experts & Organizations (1)

Associate Clinical Professor, St. John's University College of Pharmacy and Health Sciences
314 Answers
8,935 Helpful Votes

St. John's wort is an herbal supplement that has many drug interactions. In your case, it can make your simvastatin less effective, which can result in elevated cholesterol levels. It also can affect blood glucose.

I would suggest you avoid St. John's wort. If you are having symptoms of depression (a common use for St. John's wort) you should talk to your health-care professional, who can help.

This answer should not be considered medical advice...down arrowThis answer should not be considered medical advice and should not take the place of a doctor’s visit. Please see the bottom of the page for more information or visit our Terms and Conditions.up arrow

| Report This Report Answer

Was this helpful?


Thanks for your feedback.

32 of 53 found this helpful
Read the Original Article: Heart Health: Ask the Pharmacist