My WebMD Sign In, Sign Up

Ask Your Question

WebMD Answers

120 Characters remaining
120 Characters remaining
  • First, try and keep your question as short as possible.
  • Include specific words that will help us identify questions that may already have your answer.
  • If you don't find your answer, you can post your question to WebMD Experts and Contributors.


Posted: | Report This Report Question |

I take amitriptyline for headaches, and now the doctor gave me Ambien for sleep. Can I take these medications together?

Related Topics: Headache, Drug

Answers From Experts & Organizations (1)

American Pharmacists Association
239 Answers
8,672 Helpful Votes
There is a moderate drug interaction between these two medications. The disabling of the motor coordination and mental alertness is effected with one medication alone. Both medications give an additive effect, or intensify the side effects. Depending on the dose doctors worry about respiratory depression. However, if the medications are taken according to the physician's directions there shouldn't be any issues. Just be cautious of the cognitive capabilities while on both these medications.

This answer should not be considered medical advice...down arrowThis answer should not be considered medical advice and should not take the place of a doctor’s visit. Please see the bottom of the page for more information or visit our Terms and Conditions.up arrow

| Report This Report Answer

Was this helpful?


Thanks for your feedback.

22 of 31 found this helpful
Read the Original Article: Headache and Migraine Treatment: Ask the Pharmacist