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Q.

Does Soy interact with any other medications?

Related Topics: Soy, Drug
 

Answers From Experts & Organizations (1)

Medical Reference
A.
Major Interaction - Do not take this combination
  • Medications for depression (MAOIs) interacts with Soy

    Fermented soy products such as tofu and soy sauce contain tyramine. Tyramine is an amino acid that is involved in blood pressure regulation. Tyramine is broken down by monoamine oxidase. Some medications for depression (MAOIs) can decrease the breakdown of tyramine. Consuming more than 6 mg of tyramine while taking one of these medications can increase the risk of serious side effects such as blood pressure getting too high. The amount of tyramine in fermented soy products is usually small, often less than 0.6 mg per serving; however, there can be variation depending on the specific product used, storage conditions, and length of storage. Storing one brand of tofu for a week can increase tyramine content from 0.23 mg to 4.8 mg per serving. If you take one of these medications, avoid fermented soy products that contain high amounts of tyramine.
    Some of these medications include phenelzine (Nardil), tranylcypromine (Parnate), and others.

Moderate Interaction - Be cautious with this combination
  • Antibiotic drugs interacts with Soy

    Antibiotics are used to reduce harmful bacteria in the body. Antibiotics can also reduce friendly bacteria in the intestines. Friendly bacteria in the intestines seem to help increase the effectiveness of soy. By reducing the number of bacteria in intestines antibiotics might decrease the effectiveness of soy. But it is too soon to know if this interaction is a big concern.

  • Estrogens interacts with Soy

    Large amounts of soy might have some of the same effects as estrogen. But soy isn't as strong as estrogen pills. Taking soy along with estrogen pills might decrease the effects of estrogen pills.Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.

  • Tamoxifen (Nolvadex) interacts with Soy

    Some types of cancer are affected by hormones in the body. Estrogen-sensitive cancers are cancers that are affected by estrogen levels in the body. Tamoxifen (Nolvadex) is used to help treat and prevent these types of cancer. Soy seems to also affect estrogen levels in the body. By affecting estrogen in the body, soy might decrease the effectiveness of tamoxifen (Nolvadex). Do not take soy if you are taking tamoxifen (Nolvadex).

  • Warfarin (Coumadin) interacts with Soy

    Warfarin (Coumadin) is used to slow blood clotting. Soy has been reported to decrease the effectiveness of warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the risk of clotting. It is unclear why this interaction might occur. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

Minor Interaction - Be watchful of this combination
  • Medications changed by the liver (Cytochrome P450 2C9 (CYP 2C9) substrates) interacts with Soy

    Some medications are changed and broken down by the liver. Soy might increase how quickly the liver breaks down some medications. But it is too soon to know if this interaction occurs in all people or if it affects how well the medication works.

    Some medications changed by the liver include carvedilol (Coreg), fluvastatin (Lescol), losartan (Cozaar), phenytoin (Dilantin), and many others.

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Read the Original Article: More on SOY including: uses, side effects, interactions, dosages, and user reveiws.
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