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Q.

What is the recommended dosage for Melatonin?

Related Topics: Melatonin
 

Answers From Experts & Organizations (1)

Medical Reference
A.
The following doses have been studied in scientific research:

BY MOUTH:
  • For insomnia:
    • 0.3-5 mg at bedtime is a typical dose.
    • In children with insomnia due to delayed sleep onset, melatonin 5 mg at 6:00 PM daily.
    • In children with developmental disorders (including cerebral palsy, autism, and mental retardation), melatonin 5 mg at 8:00 PM daily. Both immediate-release and sustained-release preparations have been used.
  • For jet lag: 0.5-5 mg at bedtime is commonly taken on the arrival day at the destination, continuing for 2-5 days. Low doses of 0.5-3 mg are often used to avoid the hypnotic properties of the higher 4-5 mg doses.
  • For tardive dyskinesia (TD): 10 mg daily of a controlled-release formulation.
  • As treatment for solid tumors in combination with conventional therapy: 10-50 mg along with radiotherapy, chemotherapy, or interleukin 2 (IL-2). Melatonin is typically started 7 days before the start of chemotherapy and continued throughout full treatment course.
  • For treatment of prostate cancer that has spread to other sites (metastatic cancer) and is resistant to triptorelin used alone: 20 mg taken daily has been used in combination with 3.75 mg of triptorelin injected into the muscle every 28 days.
  • For prevention and treatment of lowered clot-forming cells (thrombocytopenia) associated with cancer chemotherapy: 20 mg each evening.
  • For benzodiazepine withdrawal in elderly people with insomnia: 2 mg of controlled-release melatonin taken at bedtime for 6 weeks (the benzodiazepine dosage is reduced 50% during the second week, 75% during weeks 3 and 4, and stopped during weeks 5 and 6) and continued up to 6 months.
  • For prevention of cluster headache: an evening dose of 10 mg.
  • For reducing anxiety before surgery in adults: 0.05 mg/kg under the tongue.
  • For reducing nicotine withdrawal symptoms: 0.3 mg orally 3.5 hours after stopping smoking.

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Read the Original Article: More on MELATONIN including: uses, side effects, interactions, dosages, and user reveiws.
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