If you have asthma, painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) can be risky. They include aspirin, ibuprofen, naproxen, and ketoprofen, the active ingredients in medicines like Bufferin, Advil, and Aleve. Experts aren't sure of the exact cause, but it seems that these medicines can trigger a dangerous immune response leading to constriction of the airways. In general, it's best for people with asthma to avoid NSAIDs. Other pain relievers are potentially less dangerous.
Acetaminophen -- the active ingredient in Tylenol -- poses a much lower risk of problems for people with asthma, although, like any drug, it does have side effects of its own.
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