What is the most important information I should know about Tasigna?

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What is the most important information I should know about Tasigna?

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Tasigna can cause a possible life-threatening heart problem called QTc prolongation. QTc prolongation causes an irregular heartbeat, which may lead to sudden death.

Your doctor should check the electrical activity of your heart with a test called an electrocardiogram (ECG):

Before starting Tasigna.
7 days after starting Tasigna.
With any dose changes.
Regularly during Tasigna treatment.

You may lower your chances for having QTc prolongation with Tasigna if you:

Take Tasigna:
- On an empty stomach. Do not take Tasigna with food.
- At least 2 hours after eating any food.
- Then, wait at least 1 hour before eating any food
Avoid grapefruit, grapefruit juice, and any supplement containing grapefruit extract while taking Tasigna.

Food and grapefruit products increase the amount of Tasigna in your body.

Avoid taking other medicines or supplements with Tasigna that can also cause QTc prolongation.
Tasigna can interact with many medicines and supplements and increase your chance for serious and life-threatening side effects.
Do not take any other medicine while taking Tasigna unless your doctor tells you it is okay to do so.

Call your doctor right away if you feel lightheaded, faint or have an irregular heartbeat while taking Tasigna. These can be symptoms of QTc prolongation.

This answer should not be considered medical advice...This answer should not be considered medical advice and should not take the place of a doctor’s visit. Please see the bottom of the page for more information or visit our Terms and Conditions.

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