Truvada is a type of medicine called an HIV-1 (human immunodeficiency virus) nucleoside analog reverse transcriptase inhibitor (NRTI). Truvada contains two medicines, Emtriva (emtricitabine) and Viread (tenofovir disoproxil fumarate, or tenofovir DF) combined in one pill. Truvada is always used with other anti-HIV-1 medicines to treat people with HIV-1 infection. Truvada is for adults aged 18 and older. Truvada has not been studied in children under age 18 or adults over age 65.
HIV infection destroys CD4+ T-cells, which are important to the immune system. The immune system helps fight infection. After a large number of T-cells are destroyed, acquired immune deficiency syndrome (AIDS) develops.
Truvada helps block HIV-1 reverse transcriptase, a chemical in your body (enzyme) that is needed for HIV-1 to multiply. Truvada lowers the amount of HIV-1 in the blood (viral load). Truvada may also help to increase the number of T-cells (CD4+ cells). Lowering the amount of HIV-1 in the blood lowers the chance of death or infections that happen when your immune system is weak (opportunistic infections).
Truvada does not cure HIV-1 infection or AIDS. The long-term effects of Truvada are not known at this time. People taking Truvada may still get opportunistic infections or other conditions that happen with HIV-1 infection. Opportunistic infections are infections that develop because the immune system is weak. Some of these conditions are pneumonia, herpes virus infections, andMycobacterium avium complex (MAC) infection. It is very important that you see your health care provider regularly while taking Truvada.
Truvada does not lower your chance of passing HIV-1 to other people through sexual contact, sharing needles, or being exposed to your blood. For your health and the health of others, it is important to always practice safer sex by using a latex or polyurethane condom or other barrier to lower the chance of sexual contact with semen, vaginal secretions, or blood. Never use or share dirty needles.
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